Simple and Noninvasive Breath Test Using 13C-Acetic Acid to Evaluate Gastric Emptying in Conscious Rats and Its Validation by Metoclopramide
The 13C-breath test has been used to clinically evaluate gastric emptying.However, this method has not been sufficiently validated in experimental animals.The present study aimed to establish a simple and noninvasive 13C-breath-test system in Sprague-Dawley male rats.After fasting, rats were orally administered Racol containing 13C-acetic acid and